Advanced Biology Practice Tests

These Grade 12 Science practice tests develop Advanced Biology skills through questions on cells, molecules, genetics, evolution, ecology, physiology, and experimental design.

Skills covered

  • Explaining ATP, enzymes, membranes, osmosis, organelles, gene expression, cell-cycle regulation, and homeostasis
  • Analyzing inheritance, DNA replication, mutation, PCR, gel electrophoresis, gene editing, epigenetics, and pedigrees
  • Applying natural selection, genetic drift, speciation, common ancestry, population models, energy flow, cycles, symbiosis, and biodiversity
  • Connecting nervous, endocrine, immune, renal, respiratory, circulatory, and muscular systems to physiological regulation
  • Evaluating controls, variables, replication, statistics, correlation, sample size, graphs, ethics, limitations, and conclusions

How to use these practice tests

Identify the biological process, then connect the structure, mechanism, and outcome. For data questions, distinguish what the evidence supports from claims that require additional experiments.

For more Grade 12 Science practice, return to the Grade 12 Science category.

3. Test

Grade 12 Advanced Biology Practice Tests

Practice Grade 12 Science questions about cell biology, molecular biology, genetics, evolution, ecology, physiology, and experimental design.

Choose the best answer. Apply the biological principle, connect structure to function, and interpret evidence without extending conclusions beyond the data.

10 Questions
0/10 Questions0 %
Correct 0
Incorrect 0
Unanswered 10
1. QuestionMultiple choice

What is natural selection?

Please select an answer first.

Correct answer: A

The correct answer is Heritable traits that improve reproductive success become more common over generations.

  1. Identify the biology concept: Determine whether the question concerns cells, molecules, genetics, evolution, ecology, physiology, or experimental design.
  2. Apply the biological principle: Natural selection changes populations when inherited variation affects survival or reproduction in a particular environment.
  3. Connect structure and function: The correct answer is Heritable traits that improve reproductive success become more common over generations.

Natural selection changes populations when inherited variation affects survival or reproduction in a particular environment.

2. QuestionMultiple choice

What is genetic drift?

Please select an answer first.

Correct answer: B

The correct answer is A change in allele frequencies caused by random sampling, especially in small populations.

  1. Identify the biology concept: Determine whether the question concerns cells, molecules, genetics, evolution, ecology, physiology, or experimental design.
  2. Apply the biological principle: Drift is random rather than directed and can have a strong effect when populations are small.
  3. Connect structure and function: The correct answer is A change in allele frequencies caused by random sampling, especially in small populations.

Drift is random rather than directed and can have a strong effect when populations are small.

3. QuestionMultiple choice

What can lead to speciation?

Please select an answer first.

Correct answer: C

The correct answer is Reproductive isolation that prevents gene flow between populations.

  1. Identify the biology concept: Determine whether the question concerns cells, molecules, genetics, evolution, ecology, physiology, or experimental design.
  2. Apply the biological principle: When populations no longer exchange genes and diverge over time, they may become separate species.
  3. Connect structure and function: The correct answer is Reproductive isolation that prevents gene flow between populations.

When populations no longer exchange genes and diverge over time, they may become separate species.

4. QuestionMultiple choice

What do homologous structures provide evidence for?

Please select an answer first.

Correct answer: D

The correct answer is Common ancestry despite different current functions.

  1. Identify the biology concept: Determine whether the question concerns cells, molecules, genetics, evolution, ecology, physiology, or experimental design.
  2. Apply the biological principle: Homologous structures share an underlying developmental pattern inherited from a common ancestor.
  3. Connect structure and function: The correct answer is Common ancestry despite different current functions.

Homologous structures share an underlying developmental pattern inherited from a common ancestor.

5. QuestionMultiple choice

What does the Hardy–Weinberg model describe?

Please select an answer first.

Correct answer: A

The correct answer is Allele and genotype frequencies in a population that is not evolving under specified conditions.

  1. Identify the biology concept: Determine whether the question concerns cells, molecules, genetics, evolution, ecology, physiology, or experimental design.
  2. Apply the biological principle: The model provides a baseline for detecting evolutionary change when assumptions such as random mating and no selection are considered.
  3. Connect structure and function: The correct answer is Allele and genotype frequencies in a population that is not evolving under specified conditions.

The model provides a baseline for detecting evolutionary change when assumptions such as random mating and no selection are considered.

6. QuestionMultiple choice

What is carrying capacity?

Please select an answer first.

Correct answer: B

The correct answer is The largest population an environment can sustainably support.

  1. Identify the biology concept: Determine whether the question concerns cells, molecules, genetics, evolution, ecology, physiology, or experimental design.
  2. Apply the biological principle: Resource availability, competition, predation, and other limiting factors influence carrying capacity.
  3. Connect structure and function: The correct answer is The largest population an environment can sustainably support.

Resource availability, competition, predation, and other limiting factors influence carrying capacity.

7. QuestionMultiple choice

What does an energy pyramid show?

Please select an answer first.

Correct answer: C

The correct answer is Energy generally decreases at higher trophic levels.

  1. Identify the biology concept: Determine whether the question concerns cells, molecules, genetics, evolution, ecology, physiology, or experimental design.
  2. Apply the biological principle: Much energy is lost as heat and metabolism between trophic levels, so less is available to higher consumers.
  3. Connect structure and function: The correct answer is Energy generally decreases at higher trophic levels.

Much energy is lost as heat and metabolism between trophic levels, so less is available to higher consumers.

8. QuestionMultiple choice

What role does carbon dioxide play in the carbon cycle?

Please select an answer first.

Correct answer: D

The correct answer is It is exchanged among the atmosphere, organisms, oceans, and rocks through processes such as photosynthesis and respiration.

  1. Identify the biology concept: Determine whether the question concerns cells, molecules, genetics, evolution, ecology, physiology, or experimental design.
  2. Apply the biological principle: Carbon moves through multiple reservoirs and processes, including photosynthesis, respiration, decomposition, and combustion.
  3. Connect structure and function: The correct answer is It is exchanged among the atmosphere, organisms, oceans, and rocks through processes such as photosynthesis and respiration.

Carbon moves through multiple reservoirs and processes, including photosynthesis, respiration, decomposition, and combustion.

9. QuestionMultiple choice

What is mutualism?

Please select an answer first.

Correct answer: A

The correct answer is A relationship in which both interacting species benefit.

  1. Identify the biology concept: Determine whether the question concerns cells, molecules, genetics, evolution, ecology, physiology, or experimental design.
  2. Apply the biological principle: Mutualism is one type of symbiosis and can improve access to resources, protection, or reproduction for both partners.
  3. Connect structure and function: The correct answer is A relationship in which both interacting species benefit.

Mutualism is one type of symbiosis and can improve access to resources, protection, or reproduction for both partners.

10. QuestionMultiple choice

Why is biodiversity important to ecosystem resilience?

Please select an answer first.

Correct answer: B

The correct answer is Variety can provide alternative functions and responses when conditions change.

  1. Identify the biology concept: Determine whether the question concerns cells, molecules, genetics, evolution, ecology, physiology, or experimental design.
  2. Apply the biological principle: Greater diversity can make ecosystems more capable of maintaining functions after disturbance.
  3. Connect structure and function: The correct answer is Variety can provide alternative functions and responses when conditions change.

Greater diversity can make ecosystems more capable of maintaining functions after disturbance.