Biology: Advanced Topics Practice Tests

These Grade 11 Science practice tests examine cell biology, enzymes, cell division, molecular genetics, evolution, physiology, homeostasis, ecology, biodiversity, and experimental analysis.

Skills covered

  • Connecting cell structures, membranes, enzymes, osmosis, mitosis, and cell-cycle regulation to function
  • Explaining DNA replication, transcription, translation, mutations, gene regulation, and inheritance evidence
  • Applying natural selection, genetic drift, gene flow, Hardy-Weinberg ideas, speciation, and phylogenetic reasoning
  • Analyzing homeostasis, feedback, immunity, circulation, respiration, nervous systems, and endocrine regulation
  • Interpreting energy flow, population limits, biodiversity, biomagnification, controls, uncertainty, and biological data

How to use these practice tests

Identify the biological scale first, from molecule and cell to organism, population, or ecosystem. Then connect the evidence to the relevant mechanism and distinguish correlation from a supported causal explanation.

For more Grade 11 Science practice, return to the Grade 11 Science category.

2. Test

Grade 11 Biology Advanced Topics Practice Tests

Practice Grade 11 Science questions about cell biology, molecular genetics, evolution, physiology, ecology, homeostasis, and biological data analysis.

Choose the best answer. Identify the biological scale, connect structure to function, use evidence, and distinguish observations from supported conclusions.

10 Questions
0/10 Questions0 %
Correct 0
Incorrect 0
Unanswered 10
1. QuestionMultiple choice

What is the role of DNA replication before cell division?

Please select an answer first.

Correct answer: A

The correct answer is Copying the genetic information so each daughter cell can receive it.

  1. Identify the biological system: Determine the cell process, inheritance pattern, physiological system, population, or ecosystem being described.
  2. Apply the biological principle: Replication produces a complementary copy of each DNA molecule before chromosomes are separated.
  3. Check evidence and scale: The correct answer is Copying the genetic information so each daughter cell can receive it.

Replication produces a complementary copy of each DNA molecule before chromosomes are separated.

2. QuestionMultiple choice

Which enzyme unwinds the DNA double helix during replication?

Please select an answer first.

Correct answer: B

The correct answer is Helicase.

  1. Identify the biological system: Determine the cell process, inheritance pattern, physiological system, population, or ecosystem being described.
  2. Apply the biological principle: Helicase breaks hydrogen bonds between complementary bases and opens the replication fork.
  3. Check evidence and scale: The correct answer is Helicase.

Helicase breaks hydrogen bonds between complementary bases and opens the replication fork.

3. QuestionMultiple choice

What is transcription?

Please select an answer first.

Correct answer: C

The correct answer is Using a DNA template to produce RNA.

  1. Identify the biological system: Determine the cell process, inheritance pattern, physiological system, population, or ecosystem being described.
  2. Apply the biological principle: During transcription, RNA polymerase builds an RNA strand complementary to a DNA template.
  3. Check evidence and scale: The correct answer is Using a DNA template to produce RNA.

During transcription, RNA polymerase builds an RNA strand complementary to a DNA template.

4. QuestionMultiple choice

What is translation?

Please select an answer first.

Correct answer: D

The correct answer is Using mRNA codons to assemble a polypeptide.

  1. Identify the biological system: Determine the cell process, inheritance pattern, physiological system, population, or ecosystem being described.
  2. Apply the biological principle: Ribosomes read mRNA codons and tRNAs bring amino acids in the sequence specified by the genetic code.
  3. Check evidence and scale: The correct answer is Using mRNA codons to assemble a polypeptide.

Ribosomes read mRNA codons and tRNAs bring amino acids in the sequence specified by the genetic code.

5. QuestionMultiple choice

What does a mutation represent?

Please select an answer first.

Correct answer: A

The correct answer is A change in the DNA sequence.

  1. Identify the biological system: Determine the cell process, inheritance pattern, physiological system, population, or ecosystem being described.
  2. Apply the biological principle: Mutations alter nucleotide sequence; their effects can be harmful, neutral, or beneficial depending on context.
  3. Check evidence and scale: The correct answer is A change in the DNA sequence.

Mutations alter nucleotide sequence; their effects can be harmful, neutral, or beneficial depending on context.

6. QuestionMultiple choice

What is a substitution mutation?

Please select an answer first.

Correct answer: B

The correct answer is Replacement of one nucleotide or base pair with another.

  1. Identify the biological system: Determine the cell process, inheritance pattern, physiological system, population, or ecosystem being described.
  2. Apply the biological principle: A substitution changes one base pair, and its effect depends on whether it changes a codon or protein sequence.
  3. Check evidence and scale: The correct answer is Replacement of one nucleotide or base pair with another.

A substitution changes one base pair, and its effect depends on whether it changes a codon or protein sequence.

7. QuestionMultiple choice

What is the effect of a frameshift mutation?

Please select an answer first.

Correct answer: C

The correct answer is It changes the reading frame when bases are inserted or deleted in a non-multiple of three.

  1. Identify the biological system: Determine the cell process, inheritance pattern, physiological system, population, or ecosystem being described.
  2. Apply the biological principle: An insertion or deletion that is not a multiple of three shifts downstream codon grouping and can alter much of the protein.
  3. Check evidence and scale: The correct answer is It changes the reading frame when bases are inserted or deleted in a non-multiple of three.

An insertion or deletion that is not a multiple of three shifts downstream codon grouping and can alter much of the protein.

8. QuestionMultiple choice

What is gene expression?

Please select an answer first.

Correct answer: D

The correct answer is The use of genetic information to produce a functional RNA or protein.

  1. Identify the biological system: Determine the cell process, inheritance pattern, physiological system, population, or ecosystem being described.
  2. Apply the biological principle: Gene expression includes transcription and, for protein-coding genes, translation and regulation of the resulting product.
  3. Check evidence and scale: The correct answer is The use of genetic information to produce a functional RNA or protein.

Gene expression includes transcription and, for protein-coding genes, translation and regulation of the resulting product.

9. QuestionMultiple choice

What is the purpose of a promoter in gene regulation?

Please select an answer first.

Correct answer: A

The correct answer is It is a DNA region where transcription machinery can begin transcription.

  1. Identify the biological system: Determine the cell process, inheritance pattern, physiological system, population, or ecosystem being described.
  2. Apply the biological principle: Regulatory proteins and RNA polymerase interact near promoters to control whether transcription starts.
  3. Check evidence and scale: The correct answer is It is a DNA region where transcription machinery can begin transcription.

Regulatory proteins and RNA polymerase interact near promoters to control whether transcription starts.

10. QuestionMultiple choice

What does a codon specify in translation?

Please select an answer first.

Correct answer: B

The correct answer is An amino acid or a stop signal.

  1. Identify the biological system: Determine the cell process, inheritance pattern, physiological system, population, or ecosystem being described.
  2. Apply the biological principle: Each three-base mRNA codon corresponds to an amino acid or signals termination of translation.
  3. Check evidence and scale: The correct answer is An amino acid or a stop signal.

Each three-base mRNA codon corresponds to an amino acid or signals termination of translation.